Gramicidin



Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria Bacillus brevis. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. GCDN S is an antibiotic

3D Structures of Gramicidin
Update June 2011

Gramicidin A
1nt5, 1nt6, 1nrm, 1nru, 1ng8, 1kqe, 1jno, 1jo3, 1jo4, 1mic, 1mag, 1grm - GCDN A – NMR

1tkq - GCDN A + mini-GCDN A – NMR

1av2 - GCDN A + CsCl

1gmk - GCDN A + KCNS

Gramicidin D
2xdc, 1w5u, 1bdw, 1al4, 1alx, 1alz, 2y5m, 2y6n – GCDN D

3lml, 2izq - GCDN D + iodide

1c4d - GCDN D + CsCl

Gramicidin S
1tk2 – GCDN S + subtilisin savinase – Bacillus lentus